Bone marrow stem cell transplants are more commonly called bone marrow transplants, and are familiar to most of us as a treatment for leukemia. Because bone marrow is both “home” to the immune system and the body’s factory for blood cell production, however, a safe and successful bone marrow stem cell transplant can be applied as a permanent treatment or cure for a number of both malignant and non-malignant disorders.
New evidence suggests that bone marrow stem cells may be able to differentiate into cell types that make up tissues outside of the blood, such as liver and muscle. Scientists are exploring new uses for these stem cells.
Bone marrow stem cells can be extracted directly from bones or “mobilized” to move out of the bones and into the bloodstream for donation.
Bone Marrow Stem Cells (HSC) can treat or cure:
Inherited red blood cell disorders (hemoglobinopathies)
- Sickle cell disease
Inherited rare metabolic disorders
- Enzyme deficiencies
- ADA deficiency (adenosine deaminase deficiency)
- SCID (severe combined immunodeficiency, “bubble boy disease”)
- Aplastic anemia
- Multiple Myeloma
Autoimmune disorders (more than 80, most prevalent listed below)
- Type 1 diabetes
- Rheumatoid arthritis
- Multiple sclerosis
- Crohn’s disease
Bone Marrow Stem Cells (HSC) also make it possible to create drug-free tolerance for transplanted organs and tissue and aid in the regeneration of tissues damaged by disease or age.
- Macular degeneration
- Heart muscle damaged by heart attack or disease